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Completed TRL 4 (started at 2, targeting 4)
The objective of this study is cellular sensor engineering via stable integration of fluorescently-tagged constructs for DNA damage and oxidative stress into cellular DNA. Using genetically engineered cells with cellular sensors to build long-lived human brain organoids, we will evaluate cellular sensor efficacy, resolution, sensitivity as reporters of the biological effects of simulated space radiation.
Automated reporting of the biological effects of spaceflight in deep space missions and the associated human health risks.
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This is early/mid-stage (TRL 4) — the most realistic path in is NASA SBIR/STTR, which funds small businesses and research institutions to develop technology aligned with NASA's needs (equity-free, phased funding). Check whether a current SBIR/STTR solicitation topic overlaps with this project's technology area, or contact the project directly (above) to ask.
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