Miniature TOF Mass Spectrometer with Enhanced Resolution

Zeteo Tech, Inc. proposes to design, develop and prototype a robust, small size, weight, and power (SWaP) TOF mass spectrometer with enhanced mass resolving power (m/Δm ≥ 25,000, FWHM) and practically unlimited mass range, which will allow in situ detection of organic and biomolecules in complex mixtures. It is based on a novel design of a multi-reflection TOF using microfabrication techology. The mass analyzer operates at low static voltages (a few hundred volts). Using static voltages (without pulsing) simplifies the electronics and minimizes power consumption for the proposed miniature mass spectrometer. In phase I we will complete a preliminary design of the miniature TOF mass analyzer with enhanced mass resolving power and prototype key elements of the design.

In addition to the primary application for in situ detection and unambiguous identification of amino acids, nucleobases and other prebiotic organic molecules in solid samples, the proposed technology may be used for: 1) identification of salts, and/or minerals at Mars, ocean worlds, and other bodies; 2) monitoring of chemical composition of gas samples, including atmospheric analysis.

Proposed technology may be utilized in a wide range of government and industrial applications: 1) on-site determination of pollutants in environmental samples; 2) quick reliable identification of deadly substances in complex mixtures; 3) point‐of‐care diagnostics without time‐consuming sample pretreatment.

This is early/mid-stage (TRL 3) — the most realistic path in is NASA SBIR/STTR, which funds small businesses and research institutions to develop technology aligned with NASA's needs (equity-free, phased funding). Check whether a current SBIR/STTR solicitation topic overlaps with this project's technology area, or contact the project directly (above) to ask.

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