High-sensitivity Quantum Spectrometer for Autonomous Biological Analysis

Our proposal aims to develop a cutting-edge quantum spectrometer based on Nitrogen-Vacancy (NV) centers in diamond, capable of detecting NMR signals from biological liquid samples with unprecedented sensitivity and resolution. By utilizing advanced sensing techniques and signal processing, our technology will significantly enhance the detection of weak NMR signals, which are critical for applications in molecular biology, medical diagnostics, and environmental monitoring. The funding will be used primarily for the fabrication and testing of the initial prototype, including the development of a 3D printed sensing probe, integration of NV centers in diamond, and the implementation of sensing techniques. This will involve procuring necessary materials and equipment, assembling the system, and conducting calibration and testing on initial samples to demonstrate its performance and capabilities. Our target markets include the biomedical sector, particularly for non-invasive diagnostic tools, as well as environmental testing and research laboratories that require high-sensitivity NMR spectroscopy. The technology could also have applications in the pharmaceutical industry for drug development and molecular analysis. By offering a portable, high-performance spectrometer, we aim to provide a transformative solution for these industries, enabling faster, more precise analysis of complex biological and environmental samples.

Our quantum spectrometer, based on NV centers in diamond, can significantly support NASA mission directives by providing advanced, portable, and high-sensitivity analytical tools for a range of space exploration and research applications. The technology’s ability to detect weak NMR signals with high resolution makes it ideal for analyzing biological samples in space environments, such as monitoring astronaut health through non-invasive diagnostic tools or conducting on-site biochemical analysis of extraterrestrial materials. Additionally, our spectrometer’s compact and robust design could be used in planetary exploration missions, where detecting and analyzing organic compounds or biological signatures in soil and liquid samples is critical. The enhanced sensitivity provided by our proposed device could help NASA researchers identify molecular structures in extreme environments, advancing our understanding of life-supporting conditions on other planets. This technology aligns with NASA's goals of developing innovative tools for space-based research and exploration, particularly in astrobiology, life sciences, and in situ resource utilization. Our quantum spectrometer has substantial commercialization potential in a variety of industries, leveraging its unique ability to detect weak NMR signals with high sensitivity and resolution. This capability opens up new opportunities in several key sectors, including biomedical diagnostics, pharmaceutical development, environmental monitoring, food and agriculture, and chemical/material science. a. Biomedical Diagnostics: The technology can transform non-invasive diagnostic tools, providing detailed molecular analysis of biological fluids such as blood, urine, and saliva. This could enable earlier detection of diseases like cancer, metabolic disorders, and infections. Its compact size, portability, and precision make it ideal for clinical use, point-of-care diagnostics, and remote healthcare, where fast, reliable results are crucial. b. Pharmaceutical Industry: The quantum spectrometer can be applied in drug discovery and development to study molecular interactions, protein-ligand binding, and the characterization of complex biological systems. It could accelerate the screening process, improve the accuracy of drug formulations, and support personalized medicine approaches by providing real-time insights into the molecular structure and behavior of pharmaceutical compounds. c. Environmental Monitoring: The spectrometer’s high sensitivity makes it ideal for detecting pollutants and trace chemicals in environmental samples such as water, soil, and air. It could be used for monitoring water quality, tracking pollutants, and ensuring compliance with environmental regulations. Additionally, its ability to analyze samples in real time makes it valuable for ongoing environmental protection efforts. d. Food and Agriculture: The spectrometer can be utilized in food safety, quality control, and agricultural applications. It could detect contaminants in food products, ensure compliance with safety standards, and monitor the health of crops and soils.

This is a mature technology (TRL 7+) — the realistic path in is usually NASA's Technology Transfer Program: licensing an existing NASA patent, or a Space Act Agreement to use NASA facilities/expertise directly. NASA also runs a startup licensing program with no upfront fee for companies formed to commercialize a specific NASA technology.

None of these are guaranteed paths for this specific project — TechPort itself doesn't have an "apply" button. Reaching out to the contact(s) above with a specific question is usually the fastest way to find out what's actually open.