Assessment of Otolith Function and Asymmetry as a Corollary to Critical Sensorimotor Performance in Missions of Various Durations

We propose a simple and rapid measure of otolith asymmetry -- a basic low-level neurovestibular function that is altered in spaceflight. Our assessment apparatus and procedure was developed with previous Human Research Program (HRP) support, and has undergone validation testing and is currently in use in an unrelated Department of Defense (DoD) study. It provides a measure of binocular alignment (vertical and torsional), which is a reflection of underlying otolith asymmetry. While this measure might be important in itself (since it reflects a form of central neural compensation that might be challenged in spaceflight), it could also provide a simple alternative to locomotion and posture testing if it is found to correlate with those measures.

The technology and procedures for this project are being used in DoD projects for the assessment of vestibular function in military personnel. The technology has potential clinical applications.

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