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Create a Proof of Concept Device for a Compact Multi-VCSEL Swept Source-OCT Including Associated Signal Analysis Algorithms, and Data Review Software for Deep Space Missions
Completed
TRL 3 (started at 1, targeting 3)
Description
Focused Investigation Project
Acucela Inc. will develop a Swept Source Optical Coherence Tomography (SS-OCT) Proof of Concept device, employing a unique inexpensive light source, a Vertical Cavity Surface Emitting Laser (VCSEL). Additionally, Acucela Inc. will create an alpha Phase Emulation Algorithm (PEA) that will arithmetically combine waveforms of between 2 and 4 Vertical Cavity Surface Emitting Lasers (VCSELs) with overlapping swept wavelengths, effectively creating a single wider scan SS-OCT. Acucela Inc.will also demonstrate alpha implementation of self-imaging capabilities and alpha data reviewing software that will display retinal thickness will be delivered.
Benefits
The results of this research could ultimately form the backbone of a deployable system for long term expeditionary space missions to detect and monitor treatment of Spaceflight Associated Neuro-ocular Syndrome (SANS). Current OCTs are not compatible with long term spaceflight due to their size, fragility, and inability to perform self-examination. We have demonstrated that higher resolution OCT data can be achieved using multiple VCSELs as a sweeping laser source. Our device is compact, self-imaging, and durable. Future iterations will provide imaging on the peripapillary and macular regions of the human retina.
Details
| Technology area | Human Health, Life Support, and Habitation Systems > Human Health and Performance > Medical Diagnosis and Prognosis |
| Program | Human Research Program (HRP) |
| Lead organization | Translational Research Institute for Space Health, Houston, TX |
| Start date | 2019-03-01 |
| End date | 2020-02-29 |
Project contacts
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How to get involved
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